| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-06-23 |
| タイトル |
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タイトル |
Hair and Nail-On-Chip for Bioinspired Microfluidic Device Fabrication and Biomarker Detection |
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言語 |
en |
| 言語 |
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言語 |
eng |
| キーワード |
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言語 |
en |
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キーワード |
Bioinspired devices |
| キーワード |
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言語 |
en |
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キーワード |
diagnosis |
| キーワード |
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言語 |
en |
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キーワード |
hair on chip |
| キーワード |
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言語 |
en |
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キーワード |
noninvasive detection |
| 資源タイプ |
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資源タイプ |
journal article |
| アクセス権 |
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アクセス権 |
open access |
| 著者 |
Ray, Rohitraj
Rakesh, Amith
Singh, Sheetal
マドゥエスタ, ハリーシャクマール
WEKO
7810
| en |
Madhyastha, Harishkumar
University of Miyazaki
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| ja |
マドゥエスタ, ハリーシャクマール
宮崎大学
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| ja-Kana |
マドゥエスタ, ハリーシャクマール
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Search repository
Mani, Naresh Kumar
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
The advent of biosensors has tremendously increased our potential of identifying and solving important problems in various domains, ranging from food safety and environmental analysis, to healthcare and medicine. However, one of the most prominent drawbacks of these technologies, especially in the biomedical field, is to employ conventional samples, such as blood, urine, tissue extracts and other body fluids for analysis, which suffer from the drawbacks of invasiveness, discomfort, and high costs encountered in transportation and storage, thereby hindering these products to be applied for point-of-care testing that has garnered substantial attention in recent years. Therefore, through this review, we emphasize for the first time, the applications of switching over to noninvasive sampling techniques involving hair and nails that not only circumvent most of the aforementioned limitations, but also serve as interesting alternatives in understanding the human physiology involving minimal costs, equipment and human interference when combined with rapidly advancing technologies, such as microfluidics and organ-on-a-chip to achieve miniaturization on an unprecedented scale. The coalescence between these two fields has not only led to the fabrication of novel microdevices involving hair and nails, but also function as robust biosensors for the detection of biomarkers, chemicals, metabolites and nucleic acids through noninvasive sampling. Finally, we have also elucidated a plethora of futuristic innovations that could be incorporated in such devices, such as expanding their applications in nail and hair-based drug delivery, their potential in serving as next-generation wearable sensors and integrating these devices with machine-learning for enhanced automation and decentralization. |
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言語 |
en |
| bibliographic_information |
en : Critical Reviews in Analytical Chemistry
巻 55,
号 3,
p. 434-460,
発行日 2023-12-22
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| 出版者 |
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出版者 |
Informa UK Limited |
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言語 |
en |
| ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
10408347 |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
15476510 |
| item_10001_relation_14 |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1080/10408347.2023.2291825 |
| 権利 |
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権利情報 |
© 2023 The Author(s). Published with license by Taylor & Francis Group, LLC |
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言語 |
en |
| 出版タイプ |
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出版タイプ |
VoR |
fulltext (2.9 MB)
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