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  1. 医学部
  1. 医学部
  2. 学術雑誌掲載論文  (医学部)

Effect of Hospital Arrival Time on Functional Prognosis of Stroke Patients: Japan Stroke Data Bank Over 20 Years

http://hdl.handle.net/10458/0002001316
http://hdl.handle.net/10458/0002001316
3d116071-843c-421d-a421-a25333bf35c0
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32_64753.pdf fulltext (1.2 MB)
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アイテムタイプ 学術雑誌論文 / Journal Article(1)
公開日 2025-05-25
タイトル
タイトル Effect of Hospital Arrival Time on Functional Prognosis of Stroke Patients: Japan Stroke Data Bank Over 20 Years
言語 en
言語
言語 eng
キーワード
言語 en
キーワード Intracerebral hemorrhage
キーワード
言語 en
キーワード Ischemic stroke
キーワード
言語 en
キーワード Off-hour effect
キーワード
言語 en
キーワード Subarachnoid hemorrhage
キーワード
言語 en
キーワード Weekend effect
資源タイプ
資源タイプ journal article
アクセス権
アクセス権 open access
著者 Omae, Tomoya

× Omae, Tomoya

en Omae, Tomoya
Omagari Kousei Medical Center

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中井, 陸運

× 中井, 陸運

WEKO 35309
e-Rad_Researcher 50595147

ja 中井, 陸運
宮崎大学

ja-Kana ナカイ, ミチカズ

en Nakai, Michikazu
University of Miyazaki

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Yoshimura, Sohei

× Yoshimura, Sohei

en Yoshimura, Sohei
National Cerebral and Cardiovascular Center

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Toyoda, Kazunori

× Toyoda, Kazunori

en Toyoda, Kazunori
National Cerebral and Cardiovascular Center

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Yanagisawa, Toshiharu

× Yanagisawa, Toshiharu

en Yanagisawa, Toshiharu
Omagari Kousei Medical Center

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Kobayashi, Shotai

× Kobayashi, Shotai

en Kobayashi, Shotai
Shimane University Faculty of Medicine

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Koga, Masatoshi

× Koga, Masatoshi

en Koga, Masatoshi
National Cerebral and Cardiovascular Center

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抄録
内容記述タイプ Abstract
内容記述 Aims: The impact of weekend/holiday and nighttime hospitalization on functional outcomes and long-term trends in stroke patients is unclear. We examined functional and life outcomes and changes over time.

Methods: We analyzed the clinical data of 203,176patients for hospital arrival day of week and 76,442patients for arrival times using Japan Stroke Data Bank. The endpoints were favorable outcome (Modified Rankin Scale[mRS]0-2), unfavorable outcome(mRS 5-6), and in-hospital mortality. We calculated odds ratios(OR) and 95% confidence interval(CI) of weekends/holidays and off-hours versus weekdays and on-hours for 2000-2009 and 2010-2020 using a mixed-effect multivariate model adjusted for confounding factors and evaluated interactions. Thereafter, we performed to check for year trends.

Results: All endpoints were worse in weekend/holiday admissions for all stroke and in off-hours hospitalization for total stroke(TS), ischemic stroke(IS), and intracerebral hemorrhage(ICH). The adjusted ORs for favorable outcomes of weekend/holiday admissions were TS, 0.90(0.87-0.93); IS, 0.89(0.86-0.93); ICH, 0.91(0.84-0.98) and unfavorable outcome TS, 1.04(1.002-1.08) IS, 1.06(1.01-1.11). Off-hour hospitalization had adjusted ORs for favorable outcome(TS, 0.86 [95% CI: 0.82-0.91]; IS, 0.90 [0.84-0.95]; ICH, 0.85 [0.75-0.96]), unfavorable outcome(TS, 1.14 [1.07-1.22]; IS, 1.13 [1.04-1.23]; ICH, 1.15 [1.01-1.31]), and mortality (TS, 1.15 [1.05-1.26]; IS, 1.17 [1.04-1.32]). For IS, the incidence of unfavorable outcomes during off-hours was significantly lower in 2010-2020 than in 2000-2009; after adjusting for reperfusion therapy, it was no longer significant.

Conclusion: Stroke patients admitted on weekends/holidays and off-hours had worse functional and life outcomes. Functional outcomes for off-hour admission for IS improved at 10-year intervals, possibly due to improvements in stroke care systems.
言語 en
bibliographic_information en : Journal of Atherosclerosis and Thrombosis

巻 32, 号 1, p. 70-87, 発行日 2025-01-01
出版者
出版者 Japan Atherosclerosis Society
言語 en
ISSN
収録物識別子タイプ PISSN
収録物識別子 13403478
ISSN
収録物識別子タイプ EISSN
収録物識別子 18803873
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関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.5551/jat.64753
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