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  1. 医学部
  1. 医学部
  2. 学術雑誌掲載論文  (医学部)

Maternal Death Due to Pulmonary Arterial Hypertension ― A Nationwide Survey in Japan ―

http://hdl.handle.net/10458/0002001283
http://hdl.handle.net/10458/0002001283
aafe9fb2-81e2-457f-bf81-7f2760f4e5fe
名前 / ファイル ライセンス アクション
89_CJ-24-0602.pdf fulltext (753 KB)
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アイテムタイプ 学術雑誌論文 / Journal Article(1)
公開日 2025-05-25
タイトル
タイトル Maternal Death Due to Pulmonary Arterial Hypertension ― A Nationwide Survey in Japan ―
言語 en
言語
言語 eng
キーワード
言語 en
キーワード Diagnosis
キーワード
言語 en
キーワード Mortality
キーワード
言語 en
キーワード Pregnancy
キーワード
言語 en
キーワード Pulmonary hypertension
資源タイプ
資源タイプ journal article
アクセス権
アクセス権 open access
著者 Aoki-Kamiya, Chizuko

× Aoki-Kamiya, Chizuko

en Aoki-Kamiya, Chizuko
National Cerebral and Cardiovascular Center

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桂木, 真司

× 桂木, 真司

WEKO 34852
e-Rad_Researcher 50521283

ja 桂木, 真司
宮崎大学

ja-Kana カツラギ, シンジ

en Katsuragi, Shinji
University of Miyazaki

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Shiina, Yumi

× Shiina, Yumi

en Shiina, Yumi
St. Luke's International Hospital Tokyo

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Hasegawa, Junichi

× Hasegawa, Junichi

en Hasegawa, Junichi
St. Marianna University School of Medicine

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Yoshimatsu, Jun

× Yoshimatsu, Jun

en Yoshimatsu, Jun
National Cerebral and Cardiovascular Center

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Nakai, Akihito

× Nakai, Akihito

en Nakai, Akihito
Imperial Gift Foundation

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Ishiwata, Isamu

× Ishiwata, Isamu

en Ishiwata, Isamu
Ishiwata Obstetrics and Gynecology Hospital

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Sekizawa, Akihiko

× Sekizawa, Akihiko

en Sekizawa, Akihiko
Showa University School of Medicine

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Ikeda, Tomoaki

× Ikeda, Tomoaki

en Ikeda, Tomoaki
Mie University Faculty of Medicine

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内容記述タイプ Abstract
内容記述 Background: With advances in treatment, the prognosis for pregnancies complicated by pulmonary arterial hypertension (PAH) has been improving. However, PAH-related maternal mortality remains high compared with that due to other cardiovascular diseases. The specifics of PAH-related maternal deaths under advanced medical standards are not well understood.
Methods and Results: We used the maternal death registration system established by the Japan Association of Obstetricians and Gynecologists and reviewed 6 PAH-related maternal deaths from 2010 to 2022. All women were initially diagnosed with PAH during pregnancy or immediately after childbirth. The diagnosis of PAH tended to be delayed because symptoms were not reported to healthcare providers and/or a different disease was diagnosed. Cardiogenic shock occurred antepartum in 1 woman and during delivery or within 7 days after delivery in the other 5 women. Four women were resuscitated and started on extracorporeal membrane oxygenation. Pulmonary vasodilators were initiated in 4 women, with a median duration of 8 days from PAH diagnosis to starting medication. Right heart failure was the most common cause of maternal death, with a median duration of 16 days from PAH diagnosis to maternal death.
Conclusions: All PAH-related maternal deaths occurred in women who were diagnosed with PAH after pregnancy. Diagnosing PAH and initiating pulmonary vasodilators takes considerable time, highlighting the importance of early diagnosis and early treatment.
言語 en
bibliographic_information en : Circulation Journal

巻 89, 号 1, p. 77-82, 発行日 2024-12-25
出版者
出版者 Japanese Circulation Society
言語 en
ISSN
収録物識別子タイプ PISSN
収録物識別子 13469843
ISSN
収録物識別子タイプ EISSN
収録物識別子 13474820
item_10001_relation_14
関連タイプ isVersionOf
識別子タイプ DOI
関連識別子 https://doi.org/10.1253/circj.CJ-24-0602
権利
権利情報 © 2025, THE JAPANESE CIRCULATION SOCIETY
言語 en
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出版タイプ VoR
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