| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-03-31 |
| タイトル |
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タイトル |
Lactiplantibacillus plantarum 06CC2 Enhanced the Expression of Intestinal Uric Acid Excretion Transporter in Mice |
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言語 |
en |
| 言語 |
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言語 |
eng |
| キーワード |
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言語 |
en |
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キーワード |
ATP-binding cassette transporter subfamily G member 2 (ABCG2) |
| キーワード |
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言語 |
en |
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キーワード |
Lactiplantibacillus plantarum 06CC2 |
| キーワード |
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言語 |
en |
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キーワード |
uric acid excretion |
| 資源タイプ |
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資源タイプ |
journal article |
| アクセス権 |
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アクセス権 |
open access |
| 著者 |
Nei, Shunsuke
Matsusaki, Tatsuya
Kawakubo, Hibiki
Ogawa, Kenjirou
西山, 和夫
Tsend-Ayush, Chuluunbat
Nakano, Tomoki
Takeshita, Masahiko
Shinyama, Takuo
山﨑, 正夫
WEKO
18975
e-Rad_Researcher
80381060
| ja |
山﨑, 正夫
宮崎大学
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| en |
Yamasaki, Masao
University of Miyazaki
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| ja-Kana |
ヤマサキ, マサオ
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Search repository
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| 抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
ATP-binding cassette transporter subfamily G member 2 (ABCG2) is responsible for the excretion of foreign substances, such as uric acid (UA) and indoxyl sulfate (IS), from the body. Given the importance of increased ABCG2 expression in UA excretion, we investigated the enhancement of intestinal ABCG2 expression using Lactiplantibacillus plantarum 06CC2 (LP06CC2). Mice were reared on a potassium oxonate-induced high-purine model at doses of 0.02% or 0.1% LP06CC2 for three weeks. Results showed that LP06CC2 feeding resulted in increased ABCG2 expression in the small intestine. The expression level of large intestinal ABCG2 also showed a tendency to increase, suggesting upregulation of the intestinal excretion transporter ABCG2 by LP06CC2. Overall, LP06CC2 treatment increased fecal UA excretion and showed a trend towards increased fecal excretion of IS, suggesting that LP06CC2 treatment enhanced the expression of intestinal ABCG2, thereby promoting the excretion of UA and other substances from the intestinal tract. |
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言語 |
en |
| 内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
Citation: Nei, S.; Matsusaki, T.; Kawakubo, H.; Ogawa, K.; Nishiyama, K.; Tsend-Ayush, C.; Nakano, T.; Takeshita, M.; Shinyama, T.; Yamasaki, M. Lactiplantibacillus plantarum 06CC2 Enhanced the Expression of Intestinal Uric Acid Excretion Transporter in Mice. Nutrients 2024, 16, 3042. https://doi.org/10.3390/nu16173042 |
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言語 |
en |
| bibliographic_information |
en : Nutrients
巻 16,
号 17,
p. 3042,
発行日 2024-09-09
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| 出版者 |
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出版者 |
MDPI AG |
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言語 |
en |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
2072-6643 |
| item_10001_relation_14 |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.3390/nu16173042 |
| 権利 |
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権利情報 |
© 2024 by the authors. |
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言語 |
en |
| 出版タイプ |
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出版タイプ |
VoR |
Fulltext (6.3 MB)
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