WEKO3
アイテム
Changes in coagulation factor XIII activity during resuscitation for hemorrhagic shock
http://hdl.handle.net/10458/0002000696
http://hdl.handle.net/10458/00020006962814d845-d94d-4504-bd62-eda5701d2827
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| アイテムタイプ | 学術雑誌論文 / Journal Article(1) | |||||||||||||||||||||
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| 公開日 | 2024-08-16 | |||||||||||||||||||||
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| タイトル | Changes in coagulation factor XIII activity during resuscitation for hemorrhagic shock | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
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| 言語 | eng | |||||||||||||||||||||
| キーワード | ||||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
| キーワード | blood transfusion | |||||||||||||||||||||
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| 言語 | en | |||||||||||||||||||||
| キーワード | Factor XIII | |||||||||||||||||||||
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| 言語 | en | |||||||||||||||||||||
| キーワード | fibrinogen | |||||||||||||||||||||
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| 言語 | en | |||||||||||||||||||||
| キーワード | hemorrhage | |||||||||||||||||||||
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| 言語 | en | |||||||||||||||||||||
| キーワード | shock | |||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||
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| アクセス権 | open access | |||||||||||||||||||||
| 著者 |
Yamada, Yusuke
× Yamada, Yusuke
× 安部, 智大
WEKO
28643
× Tanohata, Rina
× 落合, 秀信
WEKO
28646
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| 内容記述タイプ | Abstract | |||||||||||||||||||||
| 内容記述 | Objective: Little is known about the coagulation activity of factor XIII (FXIII) during resuscitation for hemorrhagic shock and the effects of plasma transfusions. We performed a single-center observational study to evaluate the changes in FXIII activity during resuscitation for hemorrhagic shock. Patient and Methods: Twenty-three adult patients with hemorrhagic shock were enrolled in this study. Blood samples were drawn upon arrival (T1), at the time of hemostasis completion (T2), and on day 2 (T3). Baseline and changes in FXIII activity and the proportion of patients with adequate levels of FXIII activity (FXIII activity >70%) were evaluated. The effects of plasma transfusion on these parameters were also investigated. Results: At T1, the median (interquartile range) FXIII activity was 53% (47–85%), which did not increase (T1 vs. T3: 53% [47–85%] vs. 63% [52–70%], P=0.8766). The proportion of patients with adequate FXIII activity decreased throughout the resuscitation period (T1, T2, and T3: 30, 34, and 21%, respectively). Plasma transfusion did not affect FXIII activity (T1 vs. T2, 66.4% [23.4] vs. 70.0% [16.2%], P=0.3956; T2 vs. T3, 72.0% [19.5] vs. 63.5% [8.6%], P=0.1161) or the proportion of adequate levels of FXIII activity at 44% at T2 and 27% at T3. Conclusion: FXIII activity is low during the early phase of a hemorrhagic shock. Even with plasma transfusion, FXIII levels were not adequately maintained throughout resuscitation. |
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| 言語 | en | |||||||||||||||||||||
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| 内容記述タイプ | Other | |||||||||||||||||||||
| 内容記述 | Citation: Yamada Y, Abe T, Tanohata R, Ochiai H. Changes in coagulation factor XIII activity during resuscitation for hemorrhagic shock. J Rural Med. 2024 Apr;19(2):76-82. doi: 10.2185/jrm.2023-028 |
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| 言語 | en | |||||||||||||||||||||
| 書誌情報 |
en : Journal of Rural Medicine 巻 19, 号 2, p. 76-82, 発行日 2024 |
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| 出版者 | Japanese Association of Rural Medicine | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
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| 収録物識別子タイプ | ISSN | |||||||||||||||||||||
| 収録物識別子 | 1880-487X | |||||||||||||||||||||
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| 収録物識別子タイプ | EISSN | |||||||||||||||||||||
| 収録物識別子 | 1880-4888 | |||||||||||||||||||||
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| 関連タイプ | isVersionOf | |||||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||||
| 関連識別子 | https://doi.org/10.2185/jrm.2023-028 | |||||||||||||||||||||
| 権利 | ||||||||||||||||||||||
| 権利情報 | © 2024 by THE JAPANESE ASSOCIATION OF RURAL MEDICINE | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
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| 出版タイプ | VoR | |||||||||||||||||||||
