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Plasma levels of natriuretic peptides and development of chronic kidney disease
http://hdl.handle.net/10458/0002000484
http://hdl.handle.net/10458/00020004849a870d30-aa32-4dea-b19e-de8d4297c1f1
| 名前 / ファイル | ライセンス | アクション |
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article (484 KB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||
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| 公開日 | 2024-02-03 | |||||||||||
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| タイトル | Plasma levels of natriuretic peptides and development of chronic kidney disease | |||||||||||
| 言語 | en | |||||||||||
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| 言語 | eng | |||||||||||
| キーワード | ||||||||||||
| 言語 | en | |||||||||||
| キーワード | Natriuretic peptides | |||||||||||
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| 言語 | en | |||||||||||
| キーワード | Chronic kidney disease | |||||||||||
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| 言語 | en | |||||||||||
| キーワード | General population | |||||||||||
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| 言語 | en | |||||||||||
| キーワード | Plasma level | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ | journal article | |||||||||||
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| アクセス権 | open access | |||||||||||
| 著者 |
小川, 敬之
× 小川, 敬之× 小村, 浩史× 桑迫, 健二× 北村, 和雄
WEKO
7929
× 加藤, 丈司 |
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| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | Background: Plasma levels of atrial and brain natriuretic peptides (ANP and BNP) are increased in patients with chronic kidney disease (CKD) complicated with deteriorated kidney function, but the relationship between the plasma level of ANP or BNP and the future development of CKD is unclear. Methods: We measured the plasma ANP and BNP levels of 294 local residents without CKD in a Japanese community (56.5 ± 10.4 years, mean ± S.D.), who were followed up for the development of CKD over the next 7 years. Results: Sixty-three residents developed CKD during the follow-up period, and the baseline level of plasma ANP of these residents was significantly higher than in those without CKD development. Kaplan-Meier analysis showed that the residents with higher ANP than the median value developed CKD more frequently than those with lower ANP. The association between plasma ANP level and CKD development was found to be independent of baseline estimated glomerular filtration rate by a Cox proportional hazards model, while this association became insignificant when adjusted by age; plasma ANP was significantly correlated with age. Compared with ANP, the relationship between plasma BNP and CKD development was unclear in these analyses. Conclusions: Age-related elevation of plasma ANP levels preceded the development of CKD in the general population of Japan, raising a possibility for ANP being involved in the development of CKD. |
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| 言語 | en | |||||||||||
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| 内容記述タイプ | Other | |||||||||||
| 内容記述 | Citation: Ogawa N, Komura H, Kuwasako K, Kitamura K, Kato J. Plasma levels of natriuretic peptides and development of chronic kidney disease. BMC Nephrol. 2015 Oct 24;16:171. doi: 10.1186/s12882-015-0163-9. PMID: 26499263; PMCID: PMC4620018. |
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| 言語 | en | |||||||||||
| 書誌情報 |
en : BMC Nephrology 巻 16, 号 1, p. 171, 発行日 2015-10-24 |
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| 出版者 | BioMed Central | |||||||||||
| 言語 | en | |||||||||||
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| 関連タイプ | isVersionOf | |||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | https://doi.org/10.1186/s12882-015-0163-9 | |||||||||||
| 権利 | ||||||||||||
| 言語 | en | |||||||||||
| 権利情報 | © 2015 Ogawa et al. | |||||||||||
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| 出版タイプ | VoR | |||||||||||
