{"created":"2024-01-31T05:30:32.067879+00:00","id":2000473,"links":{},"metadata":{"_buckets":{"deposit":"aacd9661-0bfc-43e2-b12d-5357686f06d1"},"_deposit":{"created_by":9,"id":"2000473","owner":"9","owners":[9],"pid":{"revision_id":0,"type":"depid","value":"2000473"},"status":"published"},"_oai":{"id":"oai:miyazaki-u.repo.nii.ac.jp:02000473","sets":["72","72:30"]},"author_link":["27589","22917","27596","22781"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"104","bibliographicPageStart":"100","bibliographicVolumeNumber":"21","bibliographic_titles":[{"bibliographic_title":"Environmental Health and Preventive Medicine","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objectives: DNA repair genes play an important role in protection against environmental and endogenous DNA damage, and constitute the first line of defense against cancer. Xeroderma pigmentosum complementation group C (XPC) is involved in the damage recognition step during nucleotide excision repair. The relationship between XPC intron11 C/A polymorphism and cancer risk has not been widely studied. Hence, this study evaluated the relationship between the XPC intron11 C/A polymorphism and prostate cancer risk.\n\nMaterials and methods: This hospital-based cohort consisted of 152 patients with prostate cancer and 142 male controls. The XPC intron11 C/A genotype was determined using the PCR-RFLP method. Medical, occupational, and cigarette-smoking history was obtained from each participant using questionnaires.\n\nResults: Logistic regression analysis revealed that compared to controls, the frequencies of the A/A and C/A genotypes were significantly higher than those of the C/C genotype in cancer patients (OR = 2.03, 95% confidence interval (CI) 1.03-3.98 and OR = 1.91, 95% CI 1.13-3.24, respectively). We also found that the frequency of the A/A genotype was significantly higher in cancer cases than in controls among non-smokers (OR = 7.7, 95% CI 1.38-42.88, compared to the C/C genotype).\n\nConclusion: We found that the XPC intron11 C/A polymorphism was associated with an increased risk of prostate cancer. Among non-smokers, the A/A genotype was significantly more prevalent in prostate cancer patients than in controls.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Citation:\nYoshino Y, Takeuchi S, Katoh T, Kuroda Y. XPC intron11 C/A polymorphism as a risk factor for prostate cancer. Environ Health Prev Med. 2016 Mar;21(2):100-4. doi: 10.1007/s12199-015-0505-z. Epub 2016 Jan 8. PMID: 26745975; PMCID: PMC4771637.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Japanese Society for Hygiene","subitem_publisher_language":"en"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1007/s12199-015-0505-z","subitem_relation_type_select":"DOI"}}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1342-078X","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"吉野, 喜裕","creatorNameLang":"ja"},{"creatorName":"ヨシノ, ヨシヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Yoshino, Yoshihiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"吉野","familyNameLang":"ja"},{"familyName":"ヨシノ","familyNameLang":"ja-Kana"},{"familyName":"Yoshino","familyNameLang":"en"}],"givenNames":[{"givenName":"喜裕","givenNameLang":"ja"},{"givenName":"ヨシヒロ","givenNameLang":"ja-Kana"},{"givenName":"Yoshihiro","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"27589","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"竹内, 昌平","creatorNameLang":"ja"},{"creatorName":"タケウチ, ショウヘイ","creatorNameLang":"ja-Kana"},{"creatorName":"Takeuchi, Shouhei","creatorNameLang":"en"}],"familyNames":[{"familyName":"竹内","familyNameLang":"ja"},{"familyName":"タケウチ","familyNameLang":"ja-Kana"},{"familyName":"Takeuchi","familyNameLang":"en"}],"givenNames":[{"givenName":"昌平","givenNameLang":"ja"},{"givenName":"ショウヘイ","givenNameLang":"ja-Kana"},{"givenName":"Shouhei","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"22917","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Katoh, Takahiko","creatorNameLang":"en"}],"familyNames":[{"familyName":"Katoh","familyNameLang":"en"}],"givenNames":[{"givenName":"Takahiko","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"27596","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kuroda, Yoshiki","creatorNameLang":"en"},{"creatorName":"黒田, 嘉紀","creatorNameLang":"ja"},{"creatorName":"クロダ, ヨシキ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Kuroda","familyNameLang":"en"},{"familyName":"黒田","familyNameLang":"ja"},{"familyName":"クロダ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Yoshiki","givenNameLang":"en"},{"givenName":"嘉紀","givenNameLang":"ja"},{"givenName":"ヨシキ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"22781","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"50234620","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=50234620"}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Cancer risk","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"DNA repair gene","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Prostate cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"XPC-PAT","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Xeroderma pigmentosum","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"XPC intron11 C/A polymorphism as a risk factor for prostate cancer","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"XPC intron11 C/A polymorphism as a risk factor for prostate cancer","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"9","path":["72","30"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-01-31"},"publish_date":"2024-01-31","publish_status":"0","recid":"2000473","relation_version_is_last":true,"title":["XPC intron11 C/A polymorphism as a risk factor for prostate cancer"],"weko_creator_id":"9","weko_shared_id":-1},"updated":"2024-05-27T04:09:55.702972+00:00"}