@article{oai:miyazaki-u.repo.nii.ac.jp:02000405, author = {NAZHAT Sayed Ahmad and Kitahara, Go and 北原, 豪 and KOZUKA Nobutoshi and MIDO Shogo and SADAWY Mohammed and ALI Hossam El-Sheikh and Osawa, Takeshi and 大澤, 健司}, issue = {2}, journal = {Journal of Veterinary Medical Science}, month = {}, note = {This study was aimed at demonstrating associations between peripheral biochemical parameters, endometrial leukocyte esterase (LE) and myeloperoxidase (MPO), and bacterial detection with the degree of endometrial inflammation, and determining the best time postpartum for diagnosing endometritis to predict subsequent fertility in dairy cows. Plasma albumin, blood urea nitrogen (BUN), total cholesterol (T-cho), NEFA, and BHBA concentrations were analyzed in 43 Holstein cows at 3, 5 and 7 weeks postpartum (W3, W5 and W7). Endometrial samples were collected at W3, W5 and W7 to examine LE and MPO activities, bacterial detection rates, and PMN% profiles. The 43 cows were divided into healthy (HE), subclinical endometritis (SE), and clinical endometritis (CE) groups, classified differently at W3, W5 and W7 based on the definitions of SE and CE for each of the three weeks pp. LE level had an association with PMN% in all weeks pp (P<0.05). Albumin and BUN levels had weak negative associations with endometrial PMN% at W3. Pathogenic bacterial detection rates were higher in the cows with endometritis at W3 and W5. Conception rate at first artificial insemination tended to be lower (P=0.057) in the cows diagnosed with endometritis at W3 than in the healthy cows. In conclusion, associations were found between endometrial LE and endometritis, but not for MPO and endometritis. Diagnosing endometritis in W3 may be the best moment to predict subsequent fertility., citation: Nazhat SA, Kitahara G, Kozuka N, Mido S, Sadawy M, Ali HE, Osawa T. Associations of periparturient plasma biochemical parameters, endometrial leukocyte esterase and myeloperoxidase, and bacterial detection with clinical and subclinical endometritis in postpartum dairy cows. J Vet Med Sci. 2018 Feb 20;80(2):302-310. doi: 10.1292/jvms.17-0478. Epub 2018 Jan 12. PMID: 29332864; PMCID: PMC5836768.}, pages = {302--310}, title = {Associations of periparturient plasma biochemical parameters, endometrial leukocyte esterase and myeloperoxidase, and bacterial detection with clinical and subclinical endometritis in postpartum dairy cows}, volume = {80}, year = {2018}, yomi = {キタハラ, ゴウ and オオサワ, タケシ} }