{"created":"2023-12-20T05:38:38.503077+00:00","id":2000396,"links":{},"metadata":{"_buckets":{"deposit":"0bf295fa-9042-4ee5-8760-bc82d191122f"},"_deposit":{"created_by":11,"id":"2000396","owner":"11","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"2000396"},"status":"published"},"_oai":{"id":"oai:miyazaki-u.repo.nii.ac.jp:02000396","sets":["76","76:64"]},"author_link":["30060","1806","5949","1808"],"control_number":"2000396","item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"27","bibliographicPageStart":"21","bibliographicVolumeNumber":"65","bibliographic_titles":[{"bibliographic_title":"Neuropeptides","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The central role of neuropeptide S (NPS), identified as the endogenous ligand for GPR154, now named neuropeptide S receptor (NPSR), has not yet been fully clarified. We examined the central role of NPS for body temperature, energy expenditure, locomotor activity and adrenal hormone secretion in rats. Intracerebroventricular (icv) injection of NPS increased body temperature in a dose-dependent manner. Energy consumption and locomotor activity were also significantly increased by icv injection of NPS. In addition, icv injection of NPS increased the peripheral blood concentration of adrenalin and corticosterone. Pretreatment with the β1- and β2-adrenergic receptor blocker timolol inhibited the NPS-induced increase of body temperature. The expression of both NPS mRNA in the brainstem and NPSR mRNA in the hypothalamus showed a nocturnal rhythm with a peak occurring during the first half of the dark period. To examine whether the endogenous NPS is involved in regulation of body temperature, NPSR antagonist SHA68 was administered one hour after darkness. SHA68 attenuated the nocturnal rise of body temperature. These results suggest that NPS contributes to the regulation of the sympathetic nervous system.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"citation:\nEnsho T, Nakahara K, Suzuki Y, Murakami N. Neuropeptide S increases motor activity and thermogenesis in the rat through sympathetic activation. Neuropeptides. 2017 Oct;65:21-27. doi: 10.1016/j.npep.2017.04.005. Epub 2017 Apr 13. PMID: 28433253.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier","subitem_publisher_language":"en"}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.npep.2017.04.005","subitem_relation_type_select":"DOI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2017 Elsevier Ltd. All rights reserved.","subitem_rights_language":"en"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"01434179","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"延生, 卓也","creatorNameLang":"ja"},{"creatorName":"エンショウ, タクヤ","creatorNameLang":"ja-Kana"},{"creatorName":"Ensho, Takuya","creatorNameLang":"en"}],"familyNames":[{"familyName":"延生","familyNameLang":"ja"},{"familyName":"エンショウ","familyNameLang":"ja-Kana"},{"familyName":"Ensho","familyNameLang":"en"}],"givenNames":[{"givenName":"卓也","givenNameLang":"ja"},{"givenName":"タクヤ","givenNameLang":"ja-Kana"},{"givenName":"Takuya","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"30060","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nakahara, Keiko","creatorNameLang":"en"},{"creatorName":"中原, 桂子","creatorNameLang":"ja"},{"creatorName":"ナカハラ, ケイコ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Nakahara","familyNameLang":"en"},{"familyName":"中原","familyNameLang":"ja"},{"familyName":"ナカハラ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Keiko","givenNameLang":"en"},{"givenName":"桂子","givenNameLang":"ja"},{"givenName":"ケイコ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"1806","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90315359","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=90315359"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"0000000106573887","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"https://isni.org/isni/0000000106573887"}],"affiliationNames":[{"affiliationName":"宮崎大学","affiliationNameLang":"ja"},{"affiliationName":"University of Miyazaki","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"鈴木, 祥広","creatorNameLang":"ja"},{"creatorName":"スズキ, ヨシヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Suzuki, Yoshihiro","creatorNameLang":"en"}],"familyNames":[{"familyName":"鈴木","familyNameLang":"ja"},{"familyName":"スズキ","familyNameLang":"ja-Kana"},{"familyName":"Suzuki","familyNameLang":"en"}],"givenNames":[{"givenName":"祥広","givenNameLang":"ja"},{"givenName":"ヨシヒロ","givenNameLang":"ja-Kana"},{"givenName":"Yoshihiro","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"5949","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90264366","nameIdentifierScheme":"e-Rad_Researcher","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=90264366"}]},{"creatorNames":[{"creatorName":"Murakami, Noboru","creatorNameLang":"en"},{"creatorName":"村上, 昇","creatorNameLang":"ja"},{"creatorName":"ムラカミ, ノボル","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Murakami","familyNameLang":"en"},{"familyName":"村上","familyNameLang":"ja"},{"familyName":"ムラカミ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Noboru","givenNameLang":"en"},{"givenName":"昇","givenNameLang":"ja"},{"givenName":"ノボル","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"1808","nameIdentifierScheme":"WEKO"}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Neuropeptide S","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Thermoregulation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Sympathetic nervous system","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Energy expenditure","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Neuropeptide S increases motor activity and thermogenesis in the rat through sympathetic activation","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Neuropeptide S increases motor activity and thermogenesis in the rat through sympathetic activation","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"11","path":["76","64"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-12-20"},"publish_date":"2023-12-20","publish_status":"0","recid":"2000396","relation_version_is_last":true,"title":["Neuropeptide S increases motor activity and thermogenesis in the rat through sympathetic activation"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2024-12-26T06:51:13.957070+00:00"}