{"created":"2023-05-15T10:54:08.688561+00:00","links":{},"metadata":{"_buckets":{"deposit":"7409649e-bdbf-4be6-8aa1-962434d66169"},"_deposit":{"id":"1593.1","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"1593.1"},"status":"published"},"_oai":{"id":"oai:miyazaki-u.repo.nii.ac.jp:00001593.1","sets":["72:30"]},"author_link":["7768","8142","8155","8158","7929"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"454","bibliographicPageStart":"449","bibliographicVolumeNumber":"34","bibliographic_titles":[{"bibliographic_title":"Renal Failure","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Aims: Several investigators have described the effect of tonsillectomy on unnary abnormalities and long-term renal survival rates in patients with IgA nephropathy （IgAN）, especially during the early-stage of the disease. However, whether tonsillectomy affects the rate of IgAN progress, even when the disease is in the advanced stage remains obscure. Methods: Forty-six of 365 patients who were histologically diagnosed with IgAN eventually reached end-stage kidney disease （ESKD） between 1981 and 2006. The periods from diagnosis to ESKD with renal-replacement therapy （RRT） were compared between patients with ESKD who had undergone tonsillectomy （n=15） as initial therapy for IgAN or not （n=31）. Relationships among risk factors, initial treatment and rates of progression to ESKD were also examined using multivariate analysis in a retrospective cohort study of the 46 patients. Results: The duration between renal biopsy and initiation of RRT was significantly extended for patients with, than without tonsillectomy （9.8 ± 6.0 vs. 5.8 ± 4.0 years, p=0.007; unpaired t-test）. The RRT-free survival advantage in patients with tonsillectomy was also evident in Kaplan-Meier curves （p=0.007 by log-rank test）. Logistic regression analysis showed that a high serum creatinine value at biopsy and severe histological damage were risk factors affecting rapid progression （within 7 years from diagnosis） to ESKD, whereas tonsillectomy apparently delayed disease progression （odds ratio, 0.09; '95% CI, 0.01-0.75; p=0.026）. Conclusion:Tonsillectomy might delay the rate of progression even when IgAN is relatively advanced, although the present study could not confirm whether it prevents progression to ESKD.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Informa Healthcare","subitem_publisher_language":"en"}]},"item_10001_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"22260382","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.3109/0886022x.2011.653775","subitem_relation_type_select":"DOI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2012 Informa Plc","subitem_rights_language":"en"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小松, 弘幸","creatorNameLang":"ja"},{"creatorName":"コマツ, ヒロユキ","creatorNameLang":"ja-Kana"},{"creatorName":"Komatsu, Hiroyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7768","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"30598339","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=30598339"}]},{"creatorNames":[{"creatorName":"藤元, 昭一","creatorNameLang":"ja"},{"creatorName":"フジモト, シヨウイチ","creatorNameLang":"ja-Kana"},{"creatorName":"Fujimoto, Shouichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"8142","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80173467","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=80173467"}]},{"creatorNames":[{"creatorName":"菊池, 正雄","creatorNameLang":"ja"},{"creatorName":"キクチ, マサオ","creatorNameLang":"ja-Kana"},{"creatorName":"Kikuchi, Masao","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"8155","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20608476","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=20608476"}]},{"creatorNames":[{"creatorName":"Sato, Yuji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"8158","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kitamura, Kazuo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7929","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"50204912","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=50204912"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-21"}],"displaytype":"detail","filename":"1470kamatsu.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"1470kamatsu.pdf","url":"https://miyazaki-u.repo.nii.ac.jp/record/1593.1/files/1470kamatsu.pdf"},"version_id":"5de42121-3dbb-43d0-b79e-8972a4ff5107"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"lgA nephropathy, glomerulonephritis, tonsillectomy, renal outcome, end-stage kidney disease","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Tonsillectomy Delays Progression of Advanced IgA Nephropathy to End-Stage Kidney Disease","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Tonsillectomy Delays Progression of Advanced IgA Nephropathy to End-Stage Kidney Disease","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"2","path":["30"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-05-30"},"publish_date":"2012-05-30","publish_status":"0","recid":"1593.1","relation_version_is_last":true,"title":["Tonsillectomy Delays Progression of Advanced IgA Nephropathy to End-Stage Kidney Disease"],"weko_creator_id":"2","weko_shared_id":2},"updated":"2025-06-01T23:44:32.352468+00:00"}