{"created":"2023-05-15T09:57:41.592531+00:00","id":1531,"links":{},"metadata":{"_buckets":{"deposit":"b81d1b8c-f2d0-4940-976d-0b5a3718143f"},"_deposit":{"created_by":5,"id":"1531","owner":"5","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"1531"},"status":"published"},"_oai":{"id":"oai:miyazaki-u.repo.nii.ac.jp:00001531","sets":["72","72:30"]},"author_link":["9416","7741","9102","9103","9104","7929","9097","7928","7742","9101"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"279","bibliographicPageStart":"275","bibliographicVolumeNumber":"121","bibliographic_titles":[{"bibliographic_title":"Thrombosis research","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Interleukin （IL）-18 plays a central role in the inflammatory cascade. We immunohistochemically assessed specimens obtained by directional coronary atherectomy （DCA） from patients with stable and unstable angina to determine whether IL-18 expression in coronary atherosclerotic lesions is related to plaque instability. We detected IL-18 immunoreactivity in coronary culprit plaques, especially in macrophages. More areas were immunopositive for IL-18 in DCA specimens from patients with unstable angina than in those with stable angina and IL-18 expression was increased in plaques containing thrombus. Furthermore, IL-18 expression significantly correlated with IFN-ホウ expression. These findings suggest that IL-18 is involved in the pathogenesis of plaque instability in human coronary arteries.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"http://www.elsevier.com/wps/find/journaldescription.cws_home/369/description","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier","subitem_publisher_language":"en"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00863148","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00493848","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Asada, Yujiro","creatorNameLang":"en"},{"creatorName":"浅田, 祐士郎","creatorNameLang":"ja"},{"creatorName":"アサダ　, ユウジロウ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Asada","familyNameLang":"en"},{"familyName":"浅田","familyNameLang":"ja"},{"familyName":"アサダ　","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Yujiro","givenNameLang":"en"},{"givenName":"祐士郎","givenNameLang":"ja"},{"givenName":"ユウジロウ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"7742","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"\t70202588","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=\t70202588"}]},{"creatorNames":[{"creatorName":"Nishihira, Kensaku","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"9097","nameIdentifierScheme":"WEKO"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"今村, 卓郎","creatorNameLang":"ja"},{"creatorName":"イマムラ, タクロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Imamura, Takuroh","creatorNameLang":"en"}],"familyNames":[{"familyName":"今村","familyNameLang":"ja"},{"familyName":"イマムラ","familyNameLang":"ja-Kana"},{"familyName":"Imamura","familyNameLang":"en"}],"givenNames":[{"givenName":"卓郎","givenNameLang":"ja"},{"givenName":"タクロウ","givenNameLang":"ja-Kana"},{"givenName":"Takuroh","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7928","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hatakeyama, Kinta","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7741","nameIdentifierScheme":"WEKO"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"0000000106573887","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"https://isni.org/isni/0000000106573887"}],"affiliationNames":[{"affiliationName":"宮崎大学","affiliationNameLang":"ja"},{"affiliationName":"University of Miyazaki","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"山下, 篤","creatorNameLang":"ja"},{"creatorName":"ヤマシタ, アツシ","creatorNameLang":"ja-Kana"},{"creatorName":"Yamashita, Atsushi","creatorNameLang":"en"}],"familyNames":[{"familyName":"山下","familyNameLang":"ja"},{"familyName":"ヤマシタ","familyNameLang":"ja-Kana"},{"familyName":"Yamashita","familyNameLang":"en"}],"givenNames":[{"givenName":"篤","givenNameLang":"ja"},{"givenName":"アツシ","givenNameLang":"ja-Kana"},{"givenName":"Atsushi","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"9416","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90372797","nameIdentifierScheme":"e-Rad_Researcher","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=90372797"}]},{"creatorNames":[{"creatorName":"Shibata, Yoshisato","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"9101","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Date, Haruhiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"9102","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Manabe, Ichiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"9103","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nagai, Ryozo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"9104","nameIdentifierScheme":"WEKO"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"0000000106573887","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"https://isni.org/isni/0000000106573887"}],"affiliationNames":[{"affiliationName":"宮崎大学","affiliationNameLang":"ja"},{"affiliationName":"University of Miyazaki","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"北村, 和雄","creatorNameLang":"ja"},{"creatorName":"キタムラ, カズオ","creatorNameLang":"ja-Kana"},{"creatorName":"Kitamura, Kazuo","creatorNameLang":"en"}],"familyNames":[{"familyName":"北村","familyNameLang":"ja"},{"familyName":"キタムラ","familyNameLang":"ja-Kana"},{"familyName":"Kitamura","familyNameLang":"en"}],"givenNames":[{"givenName":"和雄","givenNameLang":"ja"},{"givenName":"カズオ","givenNameLang":"ja-Kana"},{"givenName":"Kazuo","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"7929","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"50204912","nameIdentifierScheme":"e-Rad_Researcher","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=50204912"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-21"}],"displaytype":"detail","filename":"thrombosisresearch_asada_2007-121-2.pdf","filesize":[{"value":"389.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"thrombosisresearch asada 2007-121(2).pdf","url":"https://miyazaki-u.repo.nii.ac.jp/record/1531/files/thrombosisresearch_asada_2007-121-2.pdf"},"version_id":"5a468f2d-556a-4565-ae6c-34ee967d915f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Angina pectoris, Atherectomy, Atherothrombosis, Immunohistochemistry, Interleukin-18","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Expression of interleukin-18 in coronary plaque obtained by atherectomy from patients with stable and unstable angina","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Expression of interleukin-18 in coronary plaque obtained by atherectomy from patients with stable and unstable angina","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"5","path":["72","30"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2008-01-16"},"publish_date":"2008-01-16","publish_status":"0","recid":"1531","relation_version_is_last":true,"title":["Expression of interleukin-18 in coronary plaque obtained by atherectomy from patients with stable and unstable angina"],"weko_creator_id":"5","weko_shared_id":2},"updated":"2025-01-07T05:13:49.363280+00:00"}