{"created":"2023-05-15T10:44:56.240615+00:00","links":{},"metadata":{"_buckets":{"deposit":"63bbf129-4678-4e73-85ab-2d5b1a8edcd9"},"_deposit":{"id":"1531.1","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"1531.1"},"status":"published"},"_oai":{"id":"oai:miyazaki-u.repo.nii.ac.jp:00001531.1","sets":["72:30"]},"author_link":["7742","9097","9098","7741","9416","9101","9102","9103","9104","7929"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"279","bibliographicPageStart":"275","bibliographicVolumeNumber":"121","bibliographic_titles":[{"bibliographic_title":"Thrombosis research","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Interleukin （IL）-18 plays a central role in the inflammatory cascade. We immunohistochemically assessed specimens obtained by directional coronary atherectomy （DCA） from patients with stable and unstable angina to determine whether IL-18 expression in coronary atherosclerotic lesions is related to plaque instability. We detected IL-18 immunoreactivity in coronary culprit plaques, especially in macrophages. More areas were immunopositive for IL-18 in DCA specimens from patients with unstable angina than in those with stable angina and IL-18 expression was increased in plaques containing thrombus. Furthermore, IL-18 expression significantly correlated with IFN-ホウ expression. These findings suggest that IL-18 is involved in the pathogenesis of plaque instability in human coronary arteries.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"http://www.elsevier.com/wps/find/journaldescription.cws_home/369/description","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier","subitem_publisher_language":"en"}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00863148","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00493848","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"浅田, 祐士郎","creatorNameLang":"ja"},{"creatorName":"アサダ　, ユウジロウ","creatorNameLang":"ja-Kana"},{"creatorName":"Asada, Yujiro","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Nishihira, Kensaku","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Imamura, Takuroh","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hatakeyama, Kinta","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamashita, Atsushi","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Shibata, Yoshisato","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Date, Haruhiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Manabe, Ichiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagai, Ryozo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kitamura, Kazuo","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-21"}],"displaytype":"detail","filename":"thrombosisresearch_asada_2007-121-2.pdf","filesize":[{"value":"389.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"thrombosisresearch asada 2007-121(2).pdf","url":"https://miyazaki-u.repo.nii.ac.jp/record/1531.1/files/thrombosisresearch_asada_2007-121-2.pdf"},"version_id":"c869b3b1-cb61-4828-b410-a9a6c063353c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Angina pectoris, Atherectomy, Atherothrombosis, Immunohistochemistry, Interleukin-18","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Expression of interleukin-18 in coronary plaque obtained by atherectomy from patients with stable and unstable angina","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Expression of interleukin-18 in coronary plaque obtained by atherectomy from patients with stable and unstable angina","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"2","path":["30"],"pubdate":{"attribute_name":"公開日","attribute_value":"2008-01-16"},"publish_date":"2008-01-16","publish_status":"0","recid":"1531.1","relation_version_is_last":true,"title":["Expression of interleukin-18 in coronary plaque obtained by atherectomy from patients with stable and unstable angina"],"weko_creator_id":"2","weko_shared_id":2},"updated":"2023-07-24T04:59:28.711670+00:00"}