{"created":"2023-05-15T09:57:32.879535+00:00","id":1370,"links":{},"metadata":{"_buckets":{"deposit":"86562916-085e-4f4a-b5d9-e00d061f2424"},"_deposit":{"created_by":5,"id":"1370","owner":"5","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"1370"},"status":"published"},"_oai":{"id":"oai:miyazaki-u.repo.nii.ac.jp:00001370","sets":["72","72:30"]},"author_link":["7768","8140","8139","8160","8158","8142"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicPageEnd":"1028","bibliographicPageStart":"1023","bibliographicVolumeNumber":"43","bibliographic_titles":[{"bibliographic_title":"Internal medicine","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective : The serum IgA/C3 ratio might be considered to serve as a diagnostic marker for patients with IgA nephropathy （IgAN）, but its value as a marker of the severity of histological lesions or prognosis is unknown. \nMethods : We studied the serum IgA/C3 ratio, using standardized reference material, in 86 patients with IgAN and in 32 with non-IgAN. The patients with IgAN were divided according to the severity of histological lesions （mild IgAN, n=29 and severe IgAN, n=57） based on Japanese clinical guidelines. \nResults : The serum IgA level was significantly higher, while its C3 level was lower in patients with severe IgAN compared to those with non-IgAN. However, these levels were not different between patients with mild IgAN and non-IgAN. In contrast, the serum IgA/C3 ratio obviously differed among the three groups （2.47±0.96 vs. 3.63±1.44 vs. 4.72±1.86; p<0.01, ANOVA）. Kaplan-Meier analysis of the patients with IgAN classified according to the mean serum IgA/C3 ratio revealed that the group with high serum IgA/C3 （4.5 and above） had a significantly poorer renal outcome （p<0.05, log-rank test）, since the cumulative renal survival rate at 5 years was 84.4% vs. 100%. The ratio （%） of patients with severe IgAN in whom hematuria disappeared, was significantly higher in the low, than in the high serum IgA/C3 group （41.9% vs. 15.4%; p<0.05, t-test）. \nConclusion : The serum IgA/C3 ratio appears to reflect the histological severity of IgAN and could serve as a marker of the progression of IgAN.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Japanese Society of Internal Medicine","subitem_publisher_language":"en"}]},"item_10001_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"15609695","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2169/internalmedicine.43.1023","subitem_relation_type_select":"DOI"}}]},"item_10001_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA10827774","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09182918","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"0000000106573887","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/0000000106573887"}],"affiliationNames":[{"affiliationName":"宮崎大学","affiliationNameLang":"ja"},{"affiliationName":"University of Miyazaki","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Komatsu, Hiroyuki","creatorNameLang":"en"},{"creatorName":"小松, 弘幸","creatorNameLang":"ja"},{"creatorName":"コマツ, ヒロユキ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Komatsu","familyNameLang":"en"},{"familyName":"小松","familyNameLang":"ja"},{"familyName":"コマツ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Hiroyuki","givenNameLang":"en"},{"givenName":"弘幸","givenNameLang":"ja"},{"givenName":"ヒロユキ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"7768","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"30598339","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=30598339"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"宮崎大学","affiliationNameLang":"ja"},{"affiliationName":"University of Miyazaki","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Fujimoto, Shouichi","creatorNameLang":"en"},{"creatorName":"藤元, 昭一","creatorNameLang":"ja"},{"creatorName":"フジモト, シヨウイチ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Fujimoto","familyNameLang":"en"},{"familyName":"藤元","familyNameLang":"ja"},{"familyName":"フジモト","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Shouichi","givenNameLang":"en"},{"givenName":"昭一","givenNameLang":"ja"},{"givenName":"シヨウイチ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"8142","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80173467","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=80173467"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Hara, Seiichiro","creatorNameLang":"en"},{"creatorName":"原, 誠一郎","creatorNameLang":"ja"},{"creatorName":"ハラ, セイイチロウ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Hara","familyNameLang":"en"},{"familyName":"原","familyNameLang":"ja"},{"familyName":"ハラ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Seiichiro","givenNameLang":"en"},{"givenName":"誠一郎","givenNameLang":"ja"},{"givenName":"セイイチロウ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"8139","nameIdentifierScheme":"WEKO"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Sato, Yuji","creatorNameLang":"en"},{"creatorName":"佐藤, 祐二","creatorNameLang":"ja"},{"creatorName":"サトウ, ユウジ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Sato","familyNameLang":"en"},{"familyName":"佐藤","familyNameLang":"ja"},{"familyName":"サトウ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Yuji","givenNameLang":"en"},{"givenName":"祐二","givenNameLang":"ja"},{"givenName":"ユウジ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"8158","nameIdentifierScheme":"WEKO"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Yamada, Kazuhiro","creatorNameLang":"en"},{"creatorName":"山田, 和弘","creatorNameLang":"ja"},{"creatorName":"ヤマダ, カズヒロ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Yamada","familyNameLang":"en"},{"familyName":"山田","familyNameLang":"ja"},{"familyName":"ヤマダ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Kazuhiro","givenNameLang":"en"},{"givenName":"和弘","givenNameLang":"ja"},{"givenName":"カズヒロ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"8140","nameIdentifierScheme":"WEKO"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Eto, Tanenao","creatorNameLang":"en"},{"creatorName":"江藤, 胤尚","creatorNameLang":"ja"},{"creatorName":"エトウ, タネナオ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Eto","familyNameLang":"en"},{"familyName":"江藤","familyNameLang":"ja"},{"familyName":"エトウ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Tanenao","givenNameLang":"en"},{"givenName":"胤尚","givenNameLang":"ja"},{"givenName":"タネナオ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"8160","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-21"}],"displaytype":"detail","filename":"2065-komatsu.pdf","filesize":[{"value":"753.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"2065-komatsu.pdf","url":"https://miyazaki-u.repo.nii.ac.jp/record/1370/files/2065-komatsu.pdf"},"version_id":"96faf1f0-9145-492e-8667-8cf86e9e80f8"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"IgA nephropathy, serum IgA/C3 ratio, serum IgA, complement, hematuria","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Relationship between Serum IgA/C3 Ratio and Progression of IgA Nephropathy","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Relationship between Serum IgA/C3 Ratio and Progression of IgA Nephropathy","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"5","path":["72","30"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2009-07-08"},"publish_date":"2009-07-08","publish_status":"0","recid":"1370","relation_version_is_last":true,"title":["Relationship between Serum IgA/C3 Ratio and Progression of IgA Nephropathy"],"weko_creator_id":"5","weko_shared_id":2},"updated":"2024-07-04T07:31:55.873908+00:00"}