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ラット視交叉上核における64-kDa蛋白質の日内変動
http://hdl.handle.net/10458/1428
http://hdl.handle.net/10458/14284f4cd38b-dadb-4e2c-a708-ee33f7dfbafe
名前 / ファイル | ライセンス | アクション |
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JVMS56(1)161.pdf (510.7 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-03-27 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Circadian Oscillation of 64-kDa Polypeptide in the Rat Suprachiasmatic Nucleus | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | ラット視交叉上核における64-kDa蛋白質の日内変動 | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
キーワード | circadian rhythm, suprachiasmatic nucleus | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
著者 |
西, 理佳子
× 西, 理佳子× 村上, 昇× 丸本, 信之× 那須, 哲夫× 黒田, 治門× 江藤, 禎一× Nishi, Rikako× 丸本, 信之× 江藤, 禎一 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In cell suspensions of suprachiasmatic nucleus harvested every 3 hr from rats kept under 12 hr: 12 hr light-dark cycle and constant darkness, we have detected a Mr 64-kDa protein whose synthesis exhibits two distinct daily peaks in SDS-PAGE. Analysis of densitometer tracings revealed that the synthesis of other proteins was independent of the time of day or not reproducible. Maximum synthesis of the 64-kDa polypeptide occurred at around CT6 and CT21, which are almost coincident with the phase advance regions of circadian activity rhythm induced by anisomycin and light pulses [15], respectively. These results suggest that the 64-kDa protein in SDS-PAGE may be a part of the circadian clock mechanism. | |||||
言語 | en | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 明暗条件下及び恒常暗下で飼育されたラットから視交叉上核神経細胞を3時間間隔で調整し, 蛋白質合成を調べた. その結果, 64-kDaの蛋白質が時刻依存性に合成されることが判明した. 恒常暗下でのそれらのピーク時(CT6とCT21)は蛋白合成阻害薬のアニソミシンや光パルスで時計が前進する時刻にほぼ等しい. このことから, この視交叉上核で合成される64-kDa蛋白質は時計機構に関係しているかも知れない. | |||||
言語 | ja | |||||
書誌情報 |
en : The journal of veterinary medical science 巻 56, 号 1, p. 161-163, 発行日 1994-02-15 |
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出版者 | ||||||
言語 | en | |||||
出版者 | Japanese Society of Veterinary Science | |||||
出版者 | ||||||
言語 | ja | |||||
出版者 | 日本獣医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09167250 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10796138 | |||||
権利 | ||||||
言語 | ja | |||||
権利情報 | 日本獣医学会 | |||||
権利 | ||||||
言語 | ja | |||||
権利情報 | 本文データは学協会の許諾に基づきCiNiiから複製したものである | |||||
他の資源との関係 | ||||||
関連名称 | http://ci.nii.ac.jp/naid/110003916010/ | |||||
著者版フラグ | ||||||
出版タイプ | VoR |