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家畜正常ゲノムDNAにおけるEpidermal growth factor receptor (EGFR) geneの解析
http://hdl.handle.net/10458/1161
http://hdl.handle.net/10458/116102cbe3e8-e318-4899-9e67-d6457e3782c9
名前 / ファイル | ライセンス | アクション |
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JVMS55(2)319.pdf (295.2 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-02-08 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Proto-Oncogene of Genomic DNA, Related to the Human Epidermal Growth Factor Receptor (EGFR) Gene, from Clinically Normal Domestic Animals | |||||
タイトル | ||||||
言語 | ja | |||||
タイトル | 家畜正常ゲノムDNAにおけるEpidermal growth factor receptor (EGFR) geneの解析 | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
キーワード | epidermal growth factor receptor gene, hybridization, proto-oncogene | |||||
資源タイプ | ||||||
資源タイプ | journal article | |||||
著者 |
甲斐, 清徳
× 甲斐, 清徳× 立山, 晉× 三好, 宣彰× 山口, 良二× 内田, 和幸× Kai, Kiyonori× Miyoshi, Noriyuki× Mina, Rostami B.× Mina, Rostami B. |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Genomic DNAs of cattle, horses, pigs, dogs, cats and chickens were surveyed using Southern blot hybridization analysis, with a human EGFR cDNA fragment. Several bands with different numbers and molecular weights were observed under the condition of low stringency in the individual animal species. The bands showing DNA polymorphism were observed among bovine genomic PstI-digested DNAs from 4 individuals and EcoRI-digested genomic DNAs from 4 chickens. These results may provide basic data which are useful for analysis of tumorigenetic mechanisms in domestic animals. | |||||
言語 | en | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | ヒトEpidermal growth factor receptor (EGFR) geneを用いて牛, 馬, 豚, 犬, 猫および鶏のゲノムDNAとのサザンブロットハイブリダイゼーションを行った. 各家畜においてヒトEGFR geneに相同性を持つ遺伝子の存在が確認された. また牛ゲノムDNAのPst I消化および鶏ゲノムDNAのEco RI消化において, 遺伝子多型と考えられる個体間でのバンドの相違が確認された. 以上の結果は, 家畜の腫瘍発生とEGFRとの関係を解析する上での基礎的な知見となるであろう. | |||||
言語 | ja | |||||
書誌情報 |
en : The journal of veterinary medical science 巻 55, 号 2, p. 319-321, 発行日 1993-01-15 |
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出版者 | ||||||
言語 | en | |||||
出版者 | Japanese Society of Veterinary Science | |||||
出版者 | ||||||
言語 | ja | |||||
出版者 | 日本獣医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09167250 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10796138 | |||||
権利 | ||||||
言語 | ja | |||||
権利情報 | 日本獣医学会 | |||||
権利 | ||||||
言語 | ja | |||||
権利情報 | 本文データは学協会の許諾に基づきCiNiiから複製したものである | |||||
他の資源との関係 | ||||||
関連名称 | http://ci.nii.ac.jp/naid/110003915811/ | |||||
著者版フラグ | ||||||
出版タイプ | VoR |