Multieystic renal dysplasia was found in a 6-day-old Japanese black bull. Grossly, both kidneys were markedly small (2.0 x 3.5 cm) with numerous cysts ranging from 1 to 8 mm in diameter. Histopathologically, both kidneys consisted of many irregularly enlarged cysts, immature glomeruli, small ducts and anomalous stromal connective tissues containing focal persistent mesenchyme characterized by a proliferation of stellate cells with myxomatous area. These features are compatible with those of multicystic renal dysplasia in humans and other mammals.
生後6日齢, 雄の黒毛和種牛にmulticystic renal dysplasiaが認められた. 肉眼的に両側腎臓は, 著しく小型で(2.0×3.5cm), 直径1～8mm大の嚢胞が, 多数形成されていた. 病理組織学的には, 両側腎臓とも多数の大小嚢胞, 小型管腔, 未熟糸球体及び粘液腫状の間質と星状細胞の増殖により特徴づけられる遺残間葉組織巣などを含む豊富な間質結合織より構成されていた. 以上の所見はヒトや他の動物種におけるmulticystic renal dysplasiaの所見とほぼ一致していた.
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Multicystic Renal Dysplasia in a Japanese Black Bull
JVMS61(7)839.pdf
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